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CePA: Novel nanomedicine for alleviating MASH via mTOR repression Skip to content Menu Medical Home Life Sciences Home Become a Member Search Medical Home Life Sciences Home About Functional Food News
One-line summary: CePA, a cerium-phytic acid nanomedicine, alleviates metabolic dysfunction-associated steatohepatitis (MASH) by repressing mTOR phosphorylation, reducing hepatic lipogenesis, inflammation, and fibrosis in preclinical models.
Citations: 4 · Risk: 1 High / 0 Medium / 0 Low
Scientists reveal why non-alcoholic steatohepatitis worsens in obese people Skip to content Menu Medical Home Life Sciences Home Become a Member Search Medical Home Life Sciences Home About Functional
One-line summary: Saturated fat increases sphingosine-1-phosphate (S1P) levels in obese individuals, driving inflammation and progression of non-alcoholic steatohepatitis (NASH), unlike unsaturated fat.
Citations: 4 · Risk: 2 High / 0 Medium / 0 Low
Madrigal Expands its MASH Pipeline with Exclusive Global Licensing Agreement for Six Preclinical siRNA Programs February 11, 2026 PDF Version Company advances its leadership in MASH with an expande
One-line summary: Madrigal has expanded its MASH treatment pipeline by licensing six preclinical siRNA programs targeting genetic drivers of disease to complement its foundational therapy Rezdiffra.
Citations: 4 · Risk: 1 High / 0 Medium / 0 Low
A new, potential treatment for nonalcoholic steatohepatitis with fibrosis Skip to content Menu Medical Home Life Sciences Home Become a Member Search Medical Home Life Sciences Home About Functional F
One-line summary: A novel therapeutic approach inducing cytoglobin (CYGB) in hepatic stellate cells shows promise for treating nonalcoholic steatohepatitis (NASH) with fibrosis by mitigating oxidative DNA damage.
Citations: 4 · Risk: 1 High / 0 Medium / 0 Low
Auto-aggressive immune cells cause liver immune pathology in non-alcoholic steatohepatitis Skip to content Menu Medical Home Life Sciences Home Become a Member Search Medical Home Life Sciences Home A
One-line summary: Auto-aggressive CD8 T cells, activated by metabolic stimuli rather than pathogens, drive liver tissue destruction and pathology in non-alcoholic steatohepatitis (NASH).
Citations: 3 · Risk: 1 High / 0 Medium / 0 Low
Potential leptin therapy for nonalcoholic steatohepatitis Skip to content Menu Medical Home Life Sciences Home Become a Member Search Medical Home Life Sciences Home About Functional Food News Health
One-line summary: Leptin therapy using metreleptin shows promise in reducing liver fat and improving nonalcoholic steatohepatitis (NASH) in patients with low leptin levels, including those with partial lipodystrophy.
Citations: 4 · Risk: 1 High / 0 Medium / 0 Low
Discovery could pave the way for developing therapies to treat nonalcoholic steatohepatitis Skip to content Menu Medical Home Life Sciences Home Become a Member Search Medical Home Life Sciences Home
One-line summary: Obesity-induced cleavage and inactivation of macrophage receptor TREM2 impairs clearance of damaged hepatocytes, promoting chronic liver inflammation and nonalcoholic steatohepatitis (NASH) development.
Citations: 4 · Risk: 1 High / 0 Medium / 0 Low
Non-alcoholic steatohepatitis progression blocked by ginger essential oil Skip to content Menu Medical Home Life Sciences Home Become a Member Search Medical Home Life Sciences Home About Functional F
One-line summary: Ginger essential oil (GEO) demonstrated potential in preventing progression of non-alcoholic steatohepatitis (NASH) in a murine model by modulating inflammation, oxidative stress, and gut microbiota.
Citations: 2 · Risk: 1 High / 0 Medium / 0 Low
Nasal COVID vaccine boost increases IgA responses linked to variant neutralisation Skip to content Menu Medical Home Life Sciences Home Become a Member Search Medical Home Life Sciences Home About Fun
One-line summary: An intranasal COVID-19 vaccine booster significantly enhances mucosal secretory IgA responses, improving neutralization of variants and complementing systemic immunity.
Citations: 4 · Risk: 1 High / 1 Medium / 0 Low
How Heat Stress Affects the Human Body at the Cellular Level Skip to content Menu Medical Home Life Sciences Home Become a Member Search Medical Home Life Sciences Home About Functional Food News Heal
One-line summary: Heat stress disrupts cellular proteostasis, mitochondrial function, gene expression, and immune responses, leading to inflammation, cell death, and increased risk of multi-organ injury and chronic diseases.
Citations: 5 · Risk: 0 High / 1 Medium / 0 Low